Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBL2 All Species: 9.09
Human Site: T653 Identified Species: 16.67
UniProt: Q08999 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08999 NP_005602.3 1139 128367 T653 V T E V R A D T G G L G R S I
Chimpanzee Pan troglodytes XP_523371 1139 128318 T653 V T E V R A D T G G L G R S I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535303 1139 128252 T652 V S E V R A D T G G L G R S I
Cat Felis silvestris
Mouse Mus musculus Q64700 1135 127455 A650 V G E V R A D A G G L G R S I
Rat Rattus norvegicus O55081 1135 127799 A650 V G E V R T D A G G L G R S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520195 1071 120785 R597 A E T G G P G R S S P T S L Y
Chicken Gallus gallus Q90600 921 104417 M450 Y Y R V M E S M L K S E E E R
Frog Xenopus laevis NP_001084880 998 113114 V527 R A W T S D S V L W V H L D A
Zebra Danio Brachydanio rerio XP_002667000 970 107485 I499 K T E F S G N I A A G A G K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24472 845 96808 K374 Q P A M A G D K F E P V R N A
Honey Bee Apis mellifera XP_395096 1006 113492 I535 F Y K V I E I I V R A E D Q L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa B9GLX8 1035 114624 A564 C S A E L V V A T Y K T V T M
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LKZ3 1013 112157 K542 E L V L A T H K T I T M L F P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 97.1 N.A. 90.9 90 N.A. 79.8 21.8 43.2 53 N.A. 23.5 40.2 N.A. N.A.
Protein Similarity: 100 99.9 N.A. 98.7 N.A. 94.9 94.8 N.A. 87.1 38.3 61.2 65.5 N.A. 40.6 57.5 N.A. N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 86.6 73.3 N.A. 0 6.6 0 13.3 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 86.6 80 N.A. 0 6.6 6.6 20 N.A. 26.6 20 N.A. N.A.
Percent
Protein Identity: 20.3 N.A. N.A. 21.8 N.A. N.A.
Protein Similarity: 39.6 N.A. N.A. 39.3 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 16 0 16 31 0 24 8 8 8 8 0 0 16 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 47 0 0 0 0 0 8 8 0 % D
% Glu: 8 8 47 8 0 16 0 0 0 8 0 16 8 8 0 % E
% Phe: 8 0 0 8 0 0 0 0 8 0 0 0 0 8 0 % F
% Gly: 0 16 0 8 8 16 8 0 39 39 8 39 8 0 8 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 8 0 8 16 0 8 0 0 0 0 31 % I
% Lys: 8 0 8 0 0 0 0 16 0 8 8 0 0 8 0 % K
% Leu: 0 8 0 8 8 0 0 0 16 0 39 0 16 8 8 % L
% Met: 0 0 0 8 8 0 0 8 0 0 0 8 0 0 8 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % N
% Pro: 0 8 0 0 0 8 0 0 0 0 16 0 0 0 8 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 8 0 8 0 39 0 0 8 0 8 0 0 47 0 8 % R
% Ser: 0 16 0 0 16 0 16 0 8 8 8 0 8 39 0 % S
% Thr: 0 24 8 8 0 16 0 24 16 0 8 16 0 8 0 % T
% Val: 39 0 8 54 0 8 8 8 8 0 8 8 8 0 8 % V
% Trp: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 8 16 0 0 0 0 0 0 0 8 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _